Calculate distances and DDH estimates with GGDC 2

GGDC 2 is an updated and enhanced version of the previous GGDC 1 (still available here) with improved DDH-prediction models and additional features such as confidence-interval estimation. To the best of our knowledge, it is the only digital DDH method that provides this feature. Of all genome-based methods we are aware of, GGDC 2 yields the highest correspondence to traditional DDH (without sharing its drawbacks). Details are described in our BMC Bioinformatics study and the GGDC FAQ page.

Of course scientists want to get rid off traditional DDH ‐ digital DDH is just the best way to accomplish that!


Step 1 Choose the alignment method for finding intergenomic matches

Help (hover)

Step 2 Optional: bootstrap replicate-based confidence intervals

Calculate confidence interval for DDH prediction based on bootstrap replicates (Help)

Step 3 Choose the query genome

Step 4 Choose the reference genome(s)




Note: to select multiple files in the browse dialog use the SHIFT or CTRL button

Step 5 Your contact details


Step 6 Submit your job


Current GGDC load